AXL anticorps (pTyr698, pTyr702, pTyr703) (Alexa Fluor 680)

N° du produit ABIN4997103

Détail du produit anti-AXL anticorps (Alexa Fluor 680)

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Épitope: pTyr698, pTyr702, pTyr703

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AXL est conjugé à/à la Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of Tyr698+Tyr702+Tyr703

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur AXL

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Autre désignation: AXL+ (AXL Produits)

Synonymes: anticorps JTK11, anticorps UFO, anticorps AI323647, anticorps Ark, anticorps Tyro7, anticorps Ufo, anticorps AXL receptor tyrosine kinase, anticorps Axl receptor tyrosine kinase, anticorps AXL, anticorps Axl

Sujet:

Synonyms: Adhesion related kinase, AI323647, Ark, Axl, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming gene, AXL transforming sequence/gene, EC 2.7.10.1, JTK11, Oncogene AXL, Tyro7, Tyrosine protein kinase receptor UFO, Tyrosine-protein kinase receptor UFO, UFO, UFO_HUMAN.

Background: The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma.The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants (AXL1 and AXL2).

ID gène: 558

Pathways: Signalisation RTK, Cellular Response to Molecule of Bacterial Origin