MGMT anticorps

N° du produit ABIN534106

Détail du produit anti-MGMT anticorps

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MGMT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against recombinant MGMT.

Specificité: This antibody is specific to MGMT.

Réactivité croisée: Humain

Immunogène: Recombinant protein corresponding to human MGMT.

Clone: MT 23-2

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry (1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In buffer containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-MGMT (ABIN534106)

Cai, Xu, Cooper, Ferkowicz, Hartwell, Pollok, Kelley: "Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents." dans: Cancer research, Vol. 65, Issue 8, pp. 3319-27, (2005) (PubMed).

Zuo, Ai, Ratliff, Suen, Hanna, Brent, Fan: "O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 13, Issue 6, pp. 967-75, (2004) (PubMed).

Roth, Xu, Luo, Kelley: "Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection." dans: Cancer gene therapy, Vol. 10, Issue 8, pp. 603-10, (2003) (PubMed).

Détails sur MGMT

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Autre désignation: MGMT (MGMT Produits)

Synonymes: anticorps AGT, anticorps AI267024, anticorps Agat, anticorps O-6-methylguanine-DNA methyltransferase, anticorps MGMT, anticorps Mgmt

ID gène: 4255

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus