ABL1 anticorps (pTyr245)

N° du produit ABIN537547

Détail du produit anti-ABL1 anticorps

Antigène: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Épitope: pTyr245

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1.

Réactivité croisée: Humain

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y245 of human ABL1.

Information d'application

Indications d'application: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ABL1 (ABIN537547)

Neely, Green, LaFerla: "Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a ?-secretase-independent manner." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 8, pp. 2781-91, (2011) (PubMed).

Aichberger, Mayerhofer, Krauth, Skvara, Florian, Sonneck, Akgul, Derdak, Pickl, Wacheck, Selzer, Monia, Moriggl, Valent, Sillaber: "Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides." dans: Blood, Vol. 105, Issue 8, pp. 3303-11, (2005) (PubMed).

Kim, Cho, Yoon, Park, Kim, Lee, Chun, Kim, Lee et al.: "Interpretation of submicroscopic deletions of the BCR or ABL gene should not depend on extra signal-FISH: problems in interpretation of submicroscopic deletion of the BCR or ABL gene with extra ..." dans: Genes, chromosomes & cancer, Vol. 43, Issue 1, pp. 37-44, (2005) (PubMed).

Barnes, McIntosh, Whetton, Daley, Bentley, Baldwin: "Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation." dans: Oncogene, Vol. 24, Issue 20, pp. 3257-67, (2005) (PubMed).

Détails sur ABL1

Antigène: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Autre désignation: ABL1 (ABL1 Produits)

Synonymes: anticorps ABL, anticorps JTK7, anticorps bcr/abl, anticorps c-ABL, anticorps p150, anticorps v-abl, anticorps AI325092, anticorps Abl, anticorps E430008G22Rik, anticorps c-Abl, anticorps ABL proto-oncogene 1, non-receptor tyrosine kinase, anticorps c-abl oncogene 1, non-receptor tyrosine kinase, anticorps Tyrosine-protein kinase abl-1, anticorps ABL1, anticorps Abl1, anticorps abl-1, anticorps abl1

ID gène: 25

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism