PDGFRA anticorps (C-Term)

N° du produit ABIN544330

Détail du produit anti-PDGFRA anticorps

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFRA est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of PDGFRA.

Réactivité croisée: Humain, Souris

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PDGFRA.

Information d'application

Indications d'application: Flow Cytometry (1:10-50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-PDGFRA (ABIN544330)

Heinrich, Corless, Duensing, McGreevey, Chen, Joseph, Singer, Griffith, Haley, Town, Demetri, Fletcher, Fletcher: "PDGFRA activating mutations in gastrointestinal stromal tumors." dans: Science (New York, N.Y.), Vol. 299, Issue 5607, pp. 708-10, (2003) (PubMed).

Cools, DeAngelo, Gotlib, Stover, Legare, Cortes, Kutok, Clark, Galinsky, Griffin, Cross, Tefferi, Malone, Alam, Schrier, Schmid, Rose, Vandenberghe, Verhoef, Boogaerts, Wlodarska, Kantarjian, Marynen et al.: "A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. ..." dans: The New England journal of medicine, Vol. 348, Issue 13, pp. 1201-14, (2003) (PubMed).

Andrae, Molander, Smits, Funa, Nistér: "Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells." dans: Biochemical and biophysical research communications, Vol. 296, Issue 3, pp. 604-11, (2002) (PubMed).

Détails sur PDGFRA

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Autre désignation: CD140a / PDGFRA (PDGFRA Produits)

Synonymes: anticorps AI115593, anticorps CD140a, anticorps Pdgfr-2, anticorps APDGFR, anticorps PDGFACE, anticorps CD140A, anticorps PDGFR-2, anticorps PDGFR2, anticorps RHEPDGFRA, anticorps PDGFR, anticorps PDGFR-A, anticorps platelet derived growth factor receptor alpha, anticorps platelet derived growth factor receptor, alpha polypeptide, anticorps platelet-derived growth factor receptor, alpha polypeptide L homeolog, anticorps platelet-derived growth factor receptor, alpha polypeptide, anticorps PDGFRA, anticorps Pdgfra, anticorps pdgfra.L

ID gène: 5156

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling