PHLPP1 anticorps (N-Term)

N° du produit ABIN544485

Détail du produit anti-PHLPP1 anticorps

Antigène: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHLPP1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of PHLPP1.

Réactivité croisée: Humain

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PHLPP1.

Information d'application

Indications d'application: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-PHLPP1 (ABIN544485)

Gao, Brognard, Newton: "The phosphatase PHLPP controls the cellular levels of protein kinase C." dans: The Journal of biological chemistry, Vol. 283, Issue 10, pp. 6300-11, (2008) (PubMed).

Brognard, Sierecki, Gao, Newton: "PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms." dans: Molecular cell, Vol. 25, Issue 6, pp. 917-31, (2007) (PubMed).

Gao, Furnari, Newton: "PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth." dans: Molecular cell, Vol. 18, Issue 1, pp. 13-24, (2005) (PubMed).

Détails sur PHLPP1

Antigène: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Autre désignation: PHLPP1 (PHLPP1 Produits)

Synonymes: anticorps PHLPP, anticorps PLEKHE1, anticorps SCOP, anticorps AI836256, anticorps Phlpp, anticorps Plekhe1, anticorps mKIAA0606, anticorps Scop, anticorps PH domain and leucine rich repeat protein phosphatase 1, anticorps PHLPP1, anticorps phlpp1, anticorps Phlpp1

ID gène: 23239

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway