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Presenilin 1 anticorps (C-Term)

PSEN1 Reactivité: Humain, Souris WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN545739
  • Antigène Voir toutes Presenilin 1 (PSEN1) Anticorps
    Presenilin 1 (PSEN1)
    Épitope
    • 31
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 110
    • 90
    • 59
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 98
    • 36
    • 2
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 132
    • 8
    Polyclonal
    Conjugué
    • 49
    • 11
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Presenilin 1 est non-conjugé
    Application
    • 107
    • 52
    • 52
    • 51
    • 40
    • 18
    • 15
    • 13
    • 11
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit polyclonal antibody raised against synthetic peptide of PSEN1.
     Réactivité croisée
    Humain, Souris
    Immunogène
    A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PSEN1.
    Top Product
    Discover our top product PSEN1 Anticorps primaire
  • Indications d'application
    ELISA (1:1000)
    Western Blot (1:100-500)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In PBS (0.09 % sodium azide)
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Miklossy, Taddei, Suva, Verdile, Fonte, Fisher, Gnjec, Ghika, Suard, Mehta, McLean, Masters, Brooks, Martins: "Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease." dans: Neurobiology of aging, Vol. 24, Issue 5, pp. 655-62, (2003) (PubMed).

    Kim, Ikeuchi, Yu, Sisodia: "Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex. Evidence for differential intramembranous processing of transmembrane subatrates." dans: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 33992-4002, (2003) (PubMed).

    Marambaud, Wen, Dutt, Shioi, Takashima, Siman, Robakis: "A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations." dans: Cell, Vol. 114, Issue 5, pp. 635-45, (2003) (PubMed).

  • Antigène
    Presenilin 1 (PSEN1)
    Autre désignation
    Presenilin-1 (PSEN1 Produits)
    Synonymes
    anticorps pre1, anticorps psen, anticorps zfPS1, anticorps zf-PS1, anticorps ad3, anticorps fad, anticorps ps1, anticorps s182, anticorps X-PS-beta, anticorps X-PS-alpha, anticorps AD3, anticorps FAD, anticorps PS-1, anticorps PS1, anticorps S182, anticorps Ad3h, anticorps presenilin 1, anticorps presenilin 1 L homeolog, anticorps psen1, anticorps PSEN1, anticorps Psen1, anticorps psen1.L
    ID gène
    5663
    Pathways
    Signalisation Notch, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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