MAPK10 anticorps (Middle Region)

N° du produit ABIN5515837

Détail du produit anti-MAPK10 anticorps

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK10 est non-conjugé

Application: Western Blotting (WB)

Séquence: VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MAPK10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAPK10

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Autre désignation: MAPK10 (MAPK10 Produits)

Synonymes: anticorps MAPK10, anticorps zgc:123234, anticorps DKFZp459H0638, anticorps Jnk3, anticorps SAPKC, anticorps SAPb, anticorps Serk2, anticorps JNK3, anticorps JNK3A, anticorps PRKM10, anticorps SAPK1b, anticorps p493F12, anticorps p54bSAPK, anticorps C230008H04Rik, anticorps JNK3B1, anticorps JNK3B2, anticorps SAPK(beta), anticorps ATMPK10, anticorps MAP kinase 10, anticorps mitogen-activated protein kinase 8 S homeolog, anticorps mitogen-activated protein kinase 10, anticorps mitogen activated protein kinase 10, anticorps MAP kinase 10, anticorps mapk8.S, anticorps MAPK10, anticorps mapk10, anticorps Mapk10, anticorps MPK10

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alias Symbols: JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK

Protein Size: 167

ID gène: 5602

NCBI Accession: NM_002753, NP_002744

UniProt: P53779

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades