SUN2 anticorps (N-Term)

N° du produit ABIN5516851

Détail du produit anti-SUN2 anticorps

Antigène: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUN2 est non-conjugé

Application: Western Blotting (WB)

Séquence: RSQRLTRYSQ GDDDGSSSSG GSSVAGSQST LFKDSPLRTL KRKSSNMKRL

Attributs du produit: This is a rabbit polyclonal antibody against SUN2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SUN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SUN2

Antigène: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Autre désignation: SUN2 (SUN2 Produits)

Synonymes: anticorps UNC84B, anticorps B230369L08Rik, anticorps C030011B15, anticorps Unc84b, anticorps RGD1563141, anticorps Sad1 and UNC84 domain containing 2, anticorps SUN2, anticorps Sun2

Sujet: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1, MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity.

Alias Symbols: SUN2, FRIGG, KIAA0668, RAB5IP, UNC84B,

Protein Interaction Partner: FBXW11, NRM, BTRC, UBC, WHSC1, RPS20, RAB5B, RAB5A, TP53BP1, C9orf3, SYNE1, SYNE2, AGO3, USP20, HGS, RAB5C,

Protein Size: 717

ID gène: 25777

NCBI Accession: XP_005261558

UniProt: Q9UH99

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2