RAD51 Homolog B anticorps (Middle Region)

N° du produit ABIN5517302

Détail du produit anti-RAD51 Homolog B anticorps

Antigène: RAD51 Homolog B (Rad51B)

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 Homolog B est non-conjugé

Application: Western Blotting (WB)

Séquence: EFDAQLQGNL KERNKFLARE ASSLKYLAEE FSIPVILTNQ ITTHLSGALA

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RAD51B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAD51 Homolog B

Antigène: RAD51 Homolog B (Rad51B)

Autre désignation: RAD51B (Rad51B Produits)

Synonymes: anticorps R51H2, anticorps RAD51L1, anticorps REC2, anticorps AI553500, anticorps Rad51l1, anticorps mREC2, anticorps ATRAD51B, anticorps T17D12.12, anticorps T17D12_12, anticorps RGD1560681, anticorps rad51l1, anticorps wu:fd07f04, anticorps zgc:56581, anticorps RAD51 paralog B, anticorps DNA repair (Rad51) family protein, anticorps Rad51 DNA recombinase 2, anticorps RAD51B, anticorps Rad51b, anticorps rad51b

Sujet: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

Alias Symbols: REC2, R51H2, RAD51L1

Protein Size: 279

ID gène: 5890

NCBI Accession: NP_002868

Pathways: Réparation de l'ADN