MBTPS2 anticorps (N-Term)

N° du produit ABIN5517527

Détail du produit anti-MBTPS2 anticorps

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBTPS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VGGWTVVYLT DLVLKSSVYF KHSYEDWLEN NGLSISPFHI RWQTAVFNRA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MBTPS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MBTPS2

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Autre désignation: MBTPS2 (MBTPS2 Produits)

Synonymes: anticorps BRESEK, anticorps IFAP, anticorps KFSDX, anticorps S2P, anticorps 9630032G22Rik, anticorps AI662535, anticorps LRRGT00063, anticorps membrane bound transcription factor peptidase, site 2, anticorps membrane-bound transcription factor peptidase, site 2, anticorps MBTPS2, anticorps Mbtps2

Sujet: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

Alias Symbols: S2P, IFAP, KFSD, KFSDX, OLMSX, BRESEK

Protein Interaction Partner: UBC, ATF6B,

Protein Size: 519

ID gène: 51360

NCBI Accession: NM_015884, NP_056968

UniProt: O43462

Pathways: ER-Nucleus Signaling