PIGA anticorps (Middle Region)
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- Antigène Voir toutes PIGA Anticorps
- PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PIGA est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IICVSYTSKE NTVLRAALNP EIVSVIPNAV DPTDFTPDPF RRHDSITIVV
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PIGA
- Top Product
- Discover our top product PIGA Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
- Autre désignation
- PIGA (PIGA Produits)
- Synonymes
- anticorps GPI3, anticorps MCAHS2, anticorps PIG-A, anticorps AI194334, anticorps Pig-a, anticorps im:6911675, anticorps zgc:56589, anticorps phosphatidylinositol glycan anchor biosynthesis class A, anticorps phosphatidylinositol glycan anchor biosynthesis, class A, anticorps PIGA, anticorps Piga, anticorps piga
- Sujet
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This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.
Alias Symbols: GPI3, PNH1, PIG-A, MCAHS2
Protein Size: 484 - ID gène
- 5277
- NCBI Accession
- NM_002641, NP_002632
- UniProt
- P37287
- Pathways
- Inositol Metabolic Process
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