OAS3 anticorps (C-Term)

N° du produit ABIN5530213

Détail du produit anti-OAS3 anticorps

Antigène: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Épitope: AA 1056-1087, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAS3 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This OAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1056-1087 amino acids from the C-terminal region of human OAS3.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.56 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur OAS3

Antigène: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Autre désignation: OAS3 (OAS3 Produits)

Synonymes: anticorps p100, anticorps Oasl10, anticorps 2'-5'-oligoadenylate synthetase 3, anticorps 2'-5' oligoadenylate synthetase 3, anticorps OAS3, anticorps Oas3

Sujet: OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.

Poids moléculaire: 121 kDa

ID gène: 4940

UniProt: Q9Y6K5

Pathways: Hepatitis C