Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ALDH6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-396 amino acids from the C-terminal region of human ALDH6A1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
ALDH6A1
(Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))
anticorps MMSADHA, anticorps MMSDH, anticorps Mmsdh, anticorps cb850, anticorps wu:fb03a04, anticorps zgc:92082, anticorps 1110038I05Rik, anticorps AI314632, anticorps aldehyde dehydrogenase 6 family member A1, anticorps aldehyde dehydrogenase 6 family, member A1, anticorps aldehyde dehydrogenase 6 family member A1 L homeolog, anticorps methylmalonic acid semialdehyde dehydrogenase, anticorps methylmalonate-semialdehyde dehydrogenase (CoA acylating), anticorps aldehyde dehydrogenase family 6, subfamily A1, anticorps ALDH6A1, anticorps Aldh6a1, anticorps aldh6a1.L, anticorps CCNA_02357, anticorps aldh6a1, anticorps VAA_RS07845
Sujet
ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.