FGD4 anticorps (N-Term)

N° du produit ABIN5536855

Détail du produit anti-FGD4 anticorps

Antigène: FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

Épitope: AA 157-186, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FGD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the N-terminal region of human FGD4.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FGD4

Antigène: FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

Autre désignation: FGD4 (FGD4 Produits)

Synonymes: anticorps CMT4H, anticorps FRABP, anticorps ZFYVE6, anticorps 9030023J02Rik, anticorps 9330209B17Rik, anticorps Frabp, anticorps FYVE, RhoGEF and PH domain containing 4, anticorps FGD4, anticorps Fgd4

Sujet: This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq].

Poids moléculaire: 87 kDa

ID gène: 121512

UniProt: Q96M96

Pathways: Neurotrophin Signaling Pathway