MMP14 anticorps (N-Term)

N° du produit ABIN5537127

Détail du produit anti-MMP14 anticorps

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Épitope: AA 145-174, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the N-terminal region of human MMP14.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14 (MMP14 Produits)

Synonymes: anticorps MMP1, anticorps MMP-14, anticorps MMP-X1, anticorps MT-MMP, anticorps MT-MMP 1, anticorps MT1-MMP, anticorps MT1MMP, anticorps MTMMP1, anticorps mmp-x1, anticorps mt1-mmp, anticorps mtmmp1, anticorps AI325305, anticorps MT-MMP-1, anticorps sabe, anticorps Mt1-mmp, anticorps MT-MMPbeta, anticorps cb386, anticorps sb:cb386, anticorps wu:fb72b09, anticorps mmp14, anticorps matrix metallopeptidase 14, anticorps matrix metallopeptidase 14 (membrane-inserted), anticorps matrix metallopeptidase 14b (membrane-inserted), anticorps matrix metallopeptidase 14a (membrane-inserted), anticorps matrix metallopeptidase 14 L homeolog, anticorps MMP14, anticorps mmp14, anticorps Mmp14, anticorps mmp14b, anticorps mmp14a, anticorps mmp14.L

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.

Poids moléculaire: 66 kDa

ID gène: 4323

UniProt: P50281

Pathways: Autophagy