CYP24A1 anticorps (Internal Region)

N° du produit ABIN569640

Détail du produit anti-CYP24A1 anticorps

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Épitope: Internal Region

Reactivité: Humain, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP24A1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-RKYDIQATDN

Specificité: This antibody is expected to recognize both reported isoforms of CYP24A1 (NP_000773.2, NP_001122387.1).

Réactivité croisée (Details): Species reactivity (tested):Human, Rat.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_000773.2, NP_001122387.1. Genename: CYP24A1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CYP24A1

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Autre désignation: CYP24A1 (CYP24A1 Produits)

Synonymes: anticorps CP24, anticorps CYP24, anticorps HCAI, anticorps P450-CC24, anticorps 24-OHase, anticorps Cyp24, anticorps 25-hydroxyvitaminD324-hydroxylase, anticorps VITD12, anticorps CP450CC24, anticorps cytochrome P450 family 24 subfamily A member 1, anticorps cytochrome P450, family 24, subfamily a, polypeptide 1, anticorps cytochrome P450, family 24, subfamily A, polypeptide 1, anticorps CYP24A1, anticorps Cyp24a1

Sujet: CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.Synonyms: 24-OHase, 25-dihydroxyvitamin D(3) 24-hydroxylase, CYP24, Cytochrome P450 24A1, Cytochrome P450-CC24, Vitamin D3 24-hydroxylase, mitochondrial 1

Poids moléculaire: 51.2kDa (NP_001122387.1).

ID gène: 1591

NCBI Accession: NP_000773

UniProt: Q07973

Pathways: Metabolism of Steroid Hormones and Vitamin D