Septin 2 anticorps

N° du produit ABIN5698458

Détail du produit anti-Septin 2 anticorps

Antigène: Septin 2 (SEPT2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Immunogène: septin 2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07721(SEPT2 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur Septin 2

Antigène: Septin 2 (SEPT2)

Autre désignation: SEPT2 (SEPT2 Produits)

Synonymes: anticorps DIFF6, anticorps NEDD5, anticorps Pnutl3, anticorps hNedd5, anticorps AW208991, anticorps Nedd-5, anticorps Nedd5, anticorps mKIAA0158, anticorps Vesp11, anticorps nedd5, anticorps wu:fb52g01, anticorps wu:fb99a01, anticorps Septin-2A, anticorps Septin-A, anticorps diff6, anticorps pnutl3, anticorps sept2, anticorps septa, anticorps xlsepta, anticorps SEPT2, anticorps Sep-02, anticorps Septin-2B, anticorps hnedd5, anticorps sept2-B, anticorps Septin-2, anticorps septin 2, anticorps septin 2 L homeolog, anticorps septin 2-like, anticorps COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain, anticorps septin 2 S homeolog, anticorps SEPT2, anticorps Sept2, anticorps sept2, anticorps sept2.L, anticorps SEPT2L, anticorps sepT2, anticorps sept2.S

Sujet: Synonyms:hNedd5, NEDD 5, NEDD5, SEPT2, SEPT2/septin 2, septin 2, septin2 Background:Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex(also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

ID gène: 4735

UniProt: Q15019