RANKL anticorps (Internal Region)

N° du produit ABIN5956118

Détail du produit anti-RANKL anticorps

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANKL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: CD254,hRANKL2,ODF,OPGL,OPTB2,Osteoclast differentiation factor,Osteoprotegerin ligand,RANKL,Receptor activator of nuclear factor kappa B ligand,Receptor activator of nuclear factor kappa-B ligand,sOdf,TNF related activation induced cytokine,TNF-related activation-induced cytokine,TNF11,TNFSF 11,Tnfsf11,TRANCE,Tumor necrosis factor (ligand) superfamily member 11,Tumor necrosis factor ligand superfamily member 11,Tumor necrosis factor ligand superfamily member 11,soluble form

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human RANKL

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:40000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RANKL

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Autre désignation: RANKL (TNFSF11 Produits)

Synonymes: anticorps CD254, anticorps ODF, anticorps OPGL, anticorps OPTB2, anticorps RANKL, anticorps TRANCE, anticorps hRANKL2, anticorps sOdf, anticorps TNFSF11, anticorps Ly109l, anticorps OPG, anticorps Trance, anticorps cd254, anticorps odf, anticorps opgl, anticorps optb2, anticorps rankl, anticorps sodf, anticorps tnfsf11, anticorps trance, anticorps TNF superfamily member 11, anticorps tumor necrosis factor (ligand) superfamily, member 11, anticorps TNF receptor superfamily member 11b, anticorps TNF superfamily member 11 L homeolog, anticorps TNFSF11, anticorps Tnfsf11, anticorps TNFRSF11B, anticorps tnfsf11.L

Sujet: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Poids moléculaire: 35kDa

ID gène: 8600

UniProt: O14788

Pathways: Signalisation NF-kappaB