CBS anticorps (Internal Region)

N° du produit ABIN6260518

Détail du produit anti-CBS anticorps

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: CBS Antibody detects endogenous levels of total CBS.

Homologie: Bovine,Sheep,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CBS, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-CBS (ABIN6260518)

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." dans: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Détails sur CBS

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Autre désignation: CBS (CBS Produits)

Synonymes: anticorps hip4, anticorps GB12529, anticorps CBS, anticorps DDBDRAFT_0189727, anticorps DDBDRAFT_0191292, anticorps DDB_0189727, anticorps DDB_0191292, anticorps cbs, anticorps AI047524, anticorps AI303044, anticorps HIP4, anticorps cb442, anticorps wu:fb37g05, anticorps wu:fm61c07, anticorps wu:fq06c06, anticorps zgc:113704, anticorps cystathionine-beta-synthase L homeolog, anticorps cystathionine-beta-synthase, anticorps cystathionine beta-synthase, anticorps cystathionine beta-synthase CBS, anticorps cystathionine beta synthase, anticorps cystathionine-beta-synthase S homeolog, anticorps cystathionine-beta-synthase b, anticorps cbs.L, anticorps cbs, anticorps Cbs, anticorps CBS, anticorps CNA06170, anticorps Tb11.02.5400, anticorps cysB, anticorps LOC100635325, anticorps cbs.S, anticorps cbsb

Sujet:

Description: Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed:23981774, PubMed:20506325, PubMed:23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).

Gene: CBS

Poids moléculaire: 61kDa

ID gène: 102724560, 875

UniProt: P35520