DAAM1 anticorps (Internal Region)

N° du produit ABIN6261212

Détail du produit anti-DAAM1 anticorps

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: DAAM1 Antibody detects endogenous levels of total DAAM1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DAAM1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DAAM1

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Autre désignation: DAAM1 (DAAM1 Produits)

Synonymes: anticorps 1700066F09Rik, anticorps 2310028E21Rik, anticorps AI503486, anticorps E130308H01, anticorps mKIAA0666, anticorps daam-1, anticorps xdaam1, anticorps daam1, anticorps DAAM1, anticorps DKFZp468D0524, anticorps daam1l, anticorps fc83b10, anticorps si:ch211-87i20.1, anticorps wu:fc83b10, anticorps dishevelled associated activator of morphogenesis 1, anticorps dishevelled associated activator of morphogenesis 1 S homeolog, anticorps dishevelled associated activator of morphogenesis 1a, anticorps dishevelled associated activator of morphogenesis 1b, anticorps DAAM1, anticorps Daam1, anticorps daam1.S, anticorps daam1a, anticorps daam1, anticorps daam1b

Sujet:

Description: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). Together with DAAM2, required for myocardial maturation and sarcomere assembly (By similarity).

Gene: DAAM1

Poids moléculaire: 123 kDa

ID gène: 23002

UniProt: Q9Y4D1

Pathways: Signalisation WNT