Klotho anticorps
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- Antigène Voir toutes Klotho (KL) Anticorps
- Klotho (KL)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Klotho est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- Klotho Antibody detects endogenous levels of total Klotho
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human Klotho
- Isotype
- IgG
- Top Product
- Discover our top product KL Anticorps primaire
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- Indications d'application
- WB 1:1000-3000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- Klotho (KL)
- Autre désignation
- Klotho (KL Produits)
- Synonymes
- anticorps alpha-kl, anticorps KL, anticorps LOC100223456, anticorps klotho, anticorps Klotho, anticorps KL, anticorps Kl, anticorps kl, anticorps LOC100533542
- Sujet
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Description: May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).
Gene: KL
- Poids moléculaire
- 116kDa
- ID gène
- 9365
- UniProt
- Q9UEF7
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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