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Klotho anticorps

KL Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262853
  • Antigène Voir toutes Klotho (KL) Anticorps
    Klotho (KL)
    Reactivité
    • 30
    • 30
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 4
    • 2
    • 1
    Lapin
    Clonalité
    • 34
    • 13
    Polyclonal
    Conjugué
    • 29
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Klotho est non-conjugé
    Application
    • 33
    • 22
    • 11
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    Klotho Antibody detects endogenous levels of total Klotho
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Klotho
    Isotype
    IgG
    Top Product
    Discover our top product KL Anticorps primaire
  • Indications d'application
    WB 1:1000-3000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    Klotho (KL)
    Autre désignation
    Klotho (KL Produits)
    Synonymes
    anticorps alpha-kl, anticorps KL, anticorps LOC100223456, anticorps klotho, anticorps Klotho, anticorps KL, anticorps Kl, anticorps kl, anticorps LOC100533542
    Sujet

    Description: May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).

    Gene: KL

    Poids moléculaire
    116kDa
    ID gène
    9365
    UniProt
    Q9UEF7
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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