RYK anticorps (Internal Region)

N° du produit ABIN6264891

Détail du produit anti-RYK anticorps

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RYK est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: RYK Antibody detects endogenous levels of total RYK.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RYK, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RYK

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Autre désignation: RYK (RYK Produits)

Synonymes: anticorps RYK, anticorps jtk5, anticorps ryk1, anticorps jtk5a, anticorps d3s3195, anticorps wu:fb37b12, anticorps wu:fi05b06, anticorps zgc:158381, anticorps MGC114645, anticorps D3S3195, anticorps JTK5, anticorps JTK5A, anticorps RYK1, anticorps AW536699, anticorps ERK-3, anticorps Vik, anticorps receptor-like tyrosine kinase, anticorps receptor-like tyrosine kinase S homeolog, anticorps tyrosine-protein kinase RYK, anticorps RYK, anticorps ryk, anticorps ryk.S, anticorps LOC100541106, anticorps Ryk

Sujet:

Description: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Gene: RYK

Poids moléculaire: 68 kDa

ID gène: 6259

UniProt: P34925

Pathways: Signalisation RTK, Signalisation WNT, Regulation of Cell Size