RUNX2 anticorps (Internal Region)

N° du produit ABIN6281988

Détail du produit anti-RUNX2 anticorps

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Épitope: AA 191-240, Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX2 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: RUNX2 is a protein encoded by the RUNX2 gene which is approximately 56,6 kDa. RUNX2 is localised to the nucleus. It is involved in gene expression, transcriptional misregulation in cancer, the dendritic cell developmental lineage pathway and the notch signalling pathway. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. RUNX2 is specifically expressed in osteoblasts. Mutations in the RUNX2 gene may result in cleidocranial dysplasia. STJ96721 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of RUNX2 protein.

Specificité: RUNX2 Polyclonal Antibody detects endogenous levels of RUNX2 protein.

Attributs du produit: Rabbit polyclonal to RUNX2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human RUNX2.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
ELISA 1:20000

Commentaires:

Specifically expressed in osteoblasts.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur RUNX2

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Autre désignation: RUNX2 (RUNX2 Produits)

Synonymes: anticorps AML3, anticorps CBF-alpha-1, anticorps CBFA1, anticorps CCD, anticorps CCD1, anticorps CLCD, anticorps OSF-2, anticorps OSF2, anticorps PEA2aA, anticorps PEBP2aA, anticorps Cbf, anticorps Cbfa-1, anticorps Cbfa1, anticorps LS3, anticorps Osf2, anticorps Pebp2a1, anticorps Pebpa2a, anticorps runx2, anticorps RUNX2, anticorps ccd, anticorps aml3, anticorps ccd1, anticorps osf2, anticorps cbfa1, anticorps pea2aa, anticorps pebp2a1, anticorps pebp2a2, anticorps pebp2aa, anticorps pebp2aa1, anticorps runt related transcription factor 2, anticorps runt-related transcription factor 2a, anticorps runt-related transcription factor 2, anticorps runt related transcription factor 2 L homeolog, anticorps RUNX2, anticorps runx2a, anticorps Runx2, anticorps runx2, anticorps LOC703331, anticorps LOC100549663, anticorps runx2.L

Poids moléculaire: 56 kDa

ID gène: 860

UniProt: Q13950