GLUT4 anticorps (N-Term)
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- Antigène Voir toutes GLUT4 (SLC2A4) Anticorps
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
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Épitope
- AA 21-70, N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GLUT4 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Fonction
- Glut4 is a protein encoded by the SLC2A4 gene which is approximately 54,7 kDa. Glut4 is localised to the cell membrane and cytoplasm. It is involved in the transport of glucose, other sugars, bile salts, organic acids and metal ions and AMP-activated protein kinase signalling. This protein falls under the solute carrier family 2 and functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, it is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Glut4 is expressed in the skeletal and cardiac muscles, brown and white fat. Mutations in the SLC2A4 gene may be involved in diabetes mellitus. STJ96888 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Glut4 protein.
- Specificité
- Glut4 Polyclonal Antibody detects endogenous levels of Glut4 protein.
- Attributs du produit
- Rabbit polyclonal to Glut4.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from human Glut4.
- Isotype
- IgG
- Top Product
- Discover our top product SLC2A4 Anticorps primaire
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- Indications d'application
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WB 1:500-1:2000
ELISA 1:20000 - Commentaires
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Skeletal and cardiac muscles, brown and white fat.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- Autre désignation
- Glut4 (SLC2A4 Produits)
- Synonymes
- anticorps GLUT4, anticorps Glut-4, anticorps Glut4, anticorps glut4, anticorps slc2a4, anticorps SLC2A4, anticorps solute carrier family 2 member 4, anticorps solute carrier family 2 (facilitated glucose transporter), member 4, anticorps solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog, anticorps SLC2A4, anticorps Slc2a4, anticorps GLUT4, anticorps slc2a4.L
- ID gène
- 6517
- UniProt
- P14672
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, L'effet Warburg
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