MAPK14 anticorps (pThr180)
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- Antigène Voir toutes MAPK14 Anticorps
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
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Épitope
- AA 120-200, pThr180
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Reactivité
- Humain, Souris, Rat, Singe
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAPK14 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Fonction
- p38 is a protein encoded by the MAPK14 gene which is approximately 41,2 kDa. p38 is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the IL-2 pathway, toll-like receptor signalling pathways, the VEGF signalling pathway and 4-1BB pathway. This protein falls under the MAP kinase family. It acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. p38 is expressed in the brain, heart, placenta, pancreas and skeletal muscle. Mutations in the MAPK14 gene may result in patellar tendinitis and lumbosacral lipoma. STJ90362 was raised in rabbit. This primary antibody specifically binds to endogenous p38 protein which only binds about T180 when T180 is phosphorylated.
- Specificité
- Phospho-p38 (T180) Polyclonal Antibody detects endogenous levels of p38 protein only when phosphorylated at T180.
- Attributs du produit
- Rabbit polyclonal to Phospho-p38 (T180).
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from human p38 around the phosphorylation site of T180.
- Isotype
- IgG
- Top Product
- Discover our top product MAPK14 Anticorps primaire
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- Indications d'application
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WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000 - Commentaires
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Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
- Autre désignation
- p38 (MAPK14 Produits)
- Synonymes
- anticorps CSBP, anticorps CSBP1, anticorps CSBP2, anticorps CSPB1, anticorps EXIP, anticorps Mxi2, anticorps PRKM14, anticorps PRKM15, anticorps RK, anticorps SAPK2A, anticorps p38, anticorps p38ALPHA, anticorps CRK1, anticorps Csbp1, anticorps Csbp2, anticorps Exip, anticorps Hog, anticorps Prkm14, anticorps Prkm15, anticorps Sapk2A, anticorps p38Hog, anticorps p38alpha, anticorps p38b, anticorps zp38b, anticorps MAPK14, anticorps 186F5S, anticorps BG:DS00797.3, anticorps CG7393, anticorps D-p38, anticorps D-p38 MAPK, anticorps D-p38b, anticorps Dm p38b, anticorps Dmel\\CG7393, anticorps Dmp38b, anticorps Dp38, anticorps Dp38b, anticorps ESTS:186F5S, anticorps Mpk34C, anticorps anon-sts23, anticorps dp38b, anticorps p38 MAPK, anticorps p38 beta, anticorps p38B, anticorps p38Kb, anticorps p38beta, anticorps Crk1, anticorps p38-alpha, anticorps p38MAPK, anticorps p38a, anticorps csbp, anticorps mapk14a, anticorps mxi2, anticorps sapk2, anticorps sapk2a, anticorps AP22.98, anticorps AP22_98, anticorps ATMPK14, anticorps mitogen-activated protein kinase 14, anticorps SAPK2a, anticorps MAP kinase 14A, anticorps MAP kinase p38a, anticorps MAPK 14A, anticorps fk28c03, anticorps hm:zeh1243, anticorps wu:fk28c03, anticorps zp38a, anticorps P38C-CRK, anticorps mitogen-activated protein kinase 14, anticorps mitogen activated protein kinase 14, anticorps mitogen-activated protein kinase 14b, anticorps p38b MAP kinase, anticorps mitogen-activated protein kinase 14 S homeolog, anticorps mitogen-activated protein kinase 14a, anticorps CRK proto-oncogene, adaptor protein, anticorps MAPK14, anticorps Mapk14, anticorps mapk14b, anticorps p38b, anticorps mapk14.S, anticorps MPK14, anticorps mapk14a, anticorps CRK
- Poids moléculaire
- 38/41 kDa
- ID gène
- 1432
- UniProt
- Q16539
- Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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