IFI16 anticorps
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- Antigène Voir toutes IFI16 Anticorps
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IFI16 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human IFI16
- Isotype
- IgG
- Top Product
- Discover our top product IFI16 Anticorps primaire
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- Indications d'application
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - Commentaires
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Expressed in peripheral blood leukocytes, fibroblasts and lymphoid cells, Present in myeloid precursors (CD34+) and throughout monocyte development, but its expression is down-regulated in erythroid and polymorphonuclear precursor cells, Present in prostate, ovary and breast (at protein level)
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
- Autre désignation
- IFI16 (IFI16 Produits)
- Synonymes
- anticorps IFNGIP1, anticorps PYHIN2, anticorps IFI16, anticorps Ifitm3l, anticorps Ifitml, anticorps interferon gamma inducible protein 16, anticorps interferon induced transmembrane protein 2, anticorps myeloid cell nuclear differentiation antigen-like protein, anticorps interferon-activable protein 203, anticorps IFI16, anticorps Ifitm2, anticorps LOC100156073, anticorps LOC488622, anticorps Ifi16
- Sujet
- This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 88.256 kDa
- ID gène
- 3428
- UniProt
- Q16666
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome
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