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Parkin anticorps (AA 62-80)
PARK2
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-Parkin anticorps
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Antigène
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Parkin (PARK2)
(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
Épitope
Tous les épitopes à travers Parkin Anticorps.
AA 62-80
Reactivité
Toutes les réactivités sur Parkin Anticorps
Humain
Hôte
Toutes les hôtes sur Parkin Anticorps
Lapin
Clonalité
Toutes les clonalités sur Parkin Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Parkin Anticorps
Cet anticorp Parkin est non-conjugé
Application
Tous les applications à travers Parkin Anticorps.
Western Blotting (WB), Immunoprecipitation (IP)
Purification
Affinity purified
Immunogène
PARK2 antibody was raised in rabbit using AA 62-80 DQQSIVHIVQRPWRKGQEM of the human 52 kDa Parkin protein as the immunogen.
Isotype
IgG
Top Product
Discover our top product PARK2 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
IP: 1:250-1:1,000, WB: 1:250-1:1,000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
Lot specific
Buffer
Affinity purified IgG supplied in PBS with 0.02 % NaN3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Détails sur Parkin
(cache)
Antigène
Parkin (PARK2)
(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
Autre désignation
PARK2 (PARK2 Produits )
Synonymes
anticorps CG10523, anticorps Dmel\\CG10523, anticorps Dpark, anticorps SD01679, anticorps dpk, anticorps AR-JP, anticorps LPRS2, anticorps PDJ, anticorps PRKN, anticorps Park, anticorps Prkn, anticorps si:ch211-123f21.1, anticorps zgc:112390, anticorps pdr-1, anticorps PARK2, anticorps parkin, anticorps parkin RBR E3 ubiquitin protein ligase, anticorps Parkinson disease (autosomal recessive, juvenile) 2, parkin, anticorps park, anticorps PRKN, anticorps Prkn, anticorps prkn, anticorps CpipJ_CPIJ014867, anticorps Park2
Sujet
Mutations in the gene, Parkin (PARK2), appear to be responsible for the pathogenesis of autosomal recessive juvenile Parkinsonism. Parkin plays a role in the ubiquitin-mediated proteolytic pathway by removal and/or detoxification of abnormally folded or damaged protein. Loss of this ubiquitin ligase activity appears to be the mechanism underlying pathogenesis of Parkin.
Pathways
Autophagy , Ubiquitin Proteasome Pathway
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