TRKA anticorps

N° du produit ABIN652382

Détail du produit anti-TRKA anticorps

Antigène: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRKA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This TrkA antibody is generated from rabbits immunized with TrkA his fusion protein

Clone: RB17710

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur TRKA

Antigène: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Autre désignation: TrkA (NTRK1 Produits)

Synonymes: anticorps MTC, anticorps TRK, anticorps TRK1, anticorps TRKA, anticorps Trk-A, anticorps p140-TrkA, anticorps CDHF12, anticorps CDHR16, anticorps HSCR1, anticorps MEN2A, anticorps MEN2B, anticorps MTC1, anticorps PTC, anticorps RET-ELE1, anticorps RET51, anticorps Trk, anticorps C80751, anticorps Tkr, anticorps TrkA, anticorps trk, anticorps trka, anticorps CTRKA, anticorps trkA, anticorps neurotrophic receptor tyrosine kinase 1, anticorps ret proto-oncogene, anticorps neurotrophic tyrosine kinase, receptor, type 1, anticorps NTRK1, anticorps RET, anticorps Ntrk1, anticorps ntrk1

Sujet: TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Poids moléculaire: 87497

ID gène: 4914

NCBI Accession: NP_001007793, NP_001012331, NP_002520

UniProt: P04629

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, cAMP Metabolic Process