TRKA anticorps

N° du produit ABIN7258516

Détail du produit anti-TRKA anticorps

Antigène: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRKA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human NTRK1 (NP_002520.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TRKA

Antigène: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Autre désignation: NTRK1 (NTRK1 Produits)

Synonymes: anticorps MTC, anticorps TRK, anticorps TRK1, anticorps TRKA, anticorps Trk-A, anticorps p140-TrkA, anticorps CDHF12, anticorps CDHR16, anticorps HSCR1, anticorps MEN2A, anticorps MEN2B, anticorps MTC1, anticorps PTC, anticorps RET-ELE1, anticorps RET51, anticorps Trk, anticorps C80751, anticorps Tkr, anticorps TrkA, anticorps trk, anticorps trka, anticorps CTRKA, anticorps trkA, anticorps neurotrophic receptor tyrosine kinase 1, anticorps ret proto-oncogene, anticorps neurotrophic tyrosine kinase, receptor, type 1, anticorps NTRK1, anticorps RET, anticorps Ntrk1, anticorps ntrk1

Sujet: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Poids moléculaire:

Observed_MW: 140 kDa

Calculated_MW: 77 kDa/83 kDa/86 kDa/87 kDa

ID gène: 4914

UniProt: P04629

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, cAMP Metabolic Process