CD11c anticorps (APC)

N° du produit ABIN6655425

Détail du produit anti-CD11c anticorps (APC)

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11c est conjugé à/à la APC

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Réactivité croisée (Details): Cross reactivity with CD11c from other sources has not been tested

Purification: Allophycocyanin conjugated CD11c Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11c. Reactivity is observed against human CD11c, Baboon, Chimpanzee, Cynomolgus, and Rhesus. . Anti-CD11c is conjugated with APC under optimal conditions and the solution is free of unconjugated APC.

Immunogène:

Immunogen: Anti-CD11c Antibody (Monoclonal) was produced by repeated immunizations with CD11c antigen.

Clone: 3-9

Isotype: IgG1

Labeling Ratio: 1-2

Information d'application

Indications d'application:

Application Note: Anti-CD11c is useful for Flow Cytometry, Immunofluorescence, and Immunoprecipitation. Researchers should determine optimal titers for applications that are not stated.

Immunoprecipitation Dilution: User Optimized

Flow Cytometry Dilution: 5μL/test/1x10e5 to 1x10e8 cells

IF Microscopy Dilution: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.1 % Gelatin

0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Détails sur CD11c

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Autre désignation: CD11c (ITGAX Produits)

Synonymes: anticorps CD11C, anticorps SLEB6, anticorps RGD1561123, anticorps AI449405, anticorps Cd11c, anticorps Cr4, anticorps N418, anticorps integrin subunit alpha X, anticorps integrin alpha X, anticorps ITGAX, anticorps Itgax

Sujet:

Synonyms: Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150 95, CD11c

Background: The 3.9 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on activated neutrophils, granulocytes, some types of activated T cells and intestinal intraepithelial lymphocytes (IEL).L killing through its interactions with fibrinogen, CD54, and iC3b.

Gene Name: ITGAX

ID gène: 3687

NCBI Accession: NP_000878

UniProt: P20702

Pathways: Système du Complément, Activated T Cell Proliferation, Integrin Complex