PPARGC1B anticorps (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta)

Details for Product anti-PPARGC1B Antibody No. ABIN6944648
Antigène
  • PPARGC1B
  • 4631412G21Rik
  • Perc
  • PGC1beta
  • ERRL1
  • PERC
  • PGC-1(beta)
  • PGC1B
  • PPARG coactivator 1 beta
  • peroxisome proliferative activated receptor, gamma, coactivator 1 beta
  • PPARGC1B
  • Ppargc1b
Reactivité
Humain, Rat (Rattus)
52
30
24
19
19
19
12
Hôte
Lapin
47
4
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp PPARGC1B est non-conjugé
5
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
19
17
11
7
6
3
3
Options
Immunogène Recombinant protein within C-terminal human PGC1 beta
Clone 6H5
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PPARGC1B products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation PPARGC1B (PPARGC1B Antibody Extrait)
Sujet

Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Subcellular location: Nucleus


Synonyms: Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1B, PERC, PGC1, PGC1B, PPARGC1.
ID gène 133522
UniProt Q86YN6
Pathways AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Indications d'application WB(1:500-2000), FCM(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Date de péremption 12 months
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