PPARGC1B anticorps

N° du produit ABIN6944648

Détail du produit anti-PPARGC1B anticorps

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PPARGC1B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Réactivité croisée: Humain, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within C-terminal human PGC1 beta

Clone: 6H5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PPARGC1B

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Autre désignation: PPARGC1B (PPARGC1B Produits)

Synonymes: anticorps PPARGC1B, anticorps 4631412G21Rik, anticorps Perc, anticorps PGC1beta, anticorps ERRL1, anticorps PERC, anticorps PGC-1(beta), anticorps PGC1B, anticorps PPARG coactivator 1 beta, anticorps peroxisome proliferative activated receptor, gamma, coactivator 1 beta, anticorps PPARGC1B, anticorps Ppargc1b

Sujet:

Synonyms: Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1B, PERC, PGC1, PGC1B, PPARGC1.

Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

ID gène: 133522

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha