AATF anticorps (C-Term)

N° du produit ABIN6990405

Détail du produit anti-AATF anticorps

Antigène: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AATF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: AATF Antibody is immunoaffinity purified IgG.

Immunogène: AATF antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus of human AATF. The immunogen is located within the last 50 amino acids of AATF.

Isotype: IgG

Information d'application

Indications d'application: AATF antibody can be used for the detection of AATF by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AATF Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AATF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur AATF

Antigène: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Autre désignation: AATF (AATF Produits)

Synonymes: anticorps AATF, anticorps ded, anticorps che1, anticorps che-1, anticorps cb109, anticorps sb:cb109, anticorps wu:fc13d05, anticorps zgc:162071, anticorps CHE-1, anticorps CHE1, anticorps DED, anticorps 4933415H02Rik, anticorps 5830465M17Rik, anticorps Che-1, anticorps Trb, anticorps Ded, anticorps apoptosis antagonizing transcription factor, anticorps Apoptosis antagonizing transcription factor, anticorps apoptosis antagonizing transcription factor S homeolog, anticorps AATF, anticorps aatf, anticorps BFR2, anticorps NAEGRDRAFT_56916, anticorps Aatf, anticorps aatf.S

Sujet: AATF Antibody: AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK), a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases. AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal, features which are typical of transcription factors. AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways. Recently, it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the beta-peptide by interacting with Par-4 (prostate apoptosis response-4), another pro-apoptotic leucine zipper protein that is associated with neuronal degeneration in Alzheimer's disease (AD), suggesting that AATF may have potential therapeutic applications in both familial and sporadic forms of AD.

ID gène: 26574

NCBI Accession: NP_036270

UniProt: Q9NY61

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome