SCARB1 anticorps (N-Term)

N° du produit ABIN6991126

Détail du produit anti-SCARB1 anticorps

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Épitope: AA 70-120, N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: At least two isoforms of SCARB1 are known to exist, this antibody can detect both isoforms.

Purification: SCARB1 Antibody is affinity chromatography purified via peptide column.

Immunogène: SCARB1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SCARB1. The immunogen is located within amino acids 70 - 120 of SCARB1.

Isotype: IgG

Information d'application

Indications d'application: SCARB1 antibody can be used for detection of SCARB1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SCARB1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SCARB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SCARB1

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Autre désignation: SCARB1 (SCARB1 Produits)

Synonymes: anticorps cb1015, anticorps SCARB1, anticorps Scarb1, anticorps CD36L1, anticorps CLA-1, anticorps CLA1, anticorps HDLQTL6, anticorps SR-BI, anticorps SRB1, anticorps AI120173, anticorps CD36, anticorps Cd36l1, anticorps Cla-1, anticorps Cla1, anticorps D5Ertd460e, anticorps Hdlq1, anticorps Hlb398, anticorps SR-B1, anticorps SRBI, anticorps Srb1, anticorps mSR-BI, anticorps scavenger receptor class B, member 1, anticorps scavenger receptor class B member 1, anticorps scarb1, anticorps SCARB1, anticorps Scarb1, anticorps CpipJ_CPIJ014332, anticorps CpipJ_CPIJ019101

Sujet: SCARB1 Antibody: Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus.

Poids moléculaire: Predicted: 56, 60 kDa

Observed: 60 kDa

ID gène: 949

UniProt: Q8WTV0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome