EPM2A anticorps (C-Term)

N° du produit ABIN6991748

Détail du produit anti-EPM2A anticorps

Antigène: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Épitope: AA 190-240, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPM2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: At least four isoforms of EPM2A are known to exist, this antibody will detect all but the shortest isoform.

Purification: EPM2A Antibody is affinity chromatography purified via peptide column.

Immunogène: EPM2A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A. The immunogen is located within amino acids 190 - 240 of EPM2A.

Isotype: IgG

Information d'application

Indications d'application: EPM2A antibody can be used for detection of EPM2A by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: EPM2A Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: EPM2A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur EPM2A

Antigène: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Autre désignation: EPM2A (EPM2A Produits)

Synonymes: anticorps TG-B, anticorps Tg(TcraK,TcrbK)TG-BFlv, anticorps EPM2, anticorps MELF, anticorps laforin, anticorps EPM2A, laforin glucan phosphatase, anticorps epilepsy, progressive myoclonic epilepsy, type 2 gene alpha, anticorps EPM2A, anticorps Epm2a

Sujet: EPM2A Antibody: The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.

Poids moléculaire: 36 kDa

ID gène: 7957

NCBI Accession: NP_005661

UniProt: O95278

Pathways: Cellular Glucan Metabolic Process