PRKAA2 anticorps

N° du produit ABIN7263351

Détail du produit anti-PRKAA2 anticorps

Antigène: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAA2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human AMPKalpha2 (NP_006243.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRKAA2

Antigène: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Autre désignation: AMPKalpha2 (PRKAA2 Produits)

Synonymes: anticorps AMPK, anticorps AMPK2, anticorps AMPKa2, anticorps PRKAA, anticorps Ampk, anticorps Ampka2, anticorps 2310008I11Rik, anticorps A830082D05, anticorps AMPKalpha2, anticorps AMPKA2, anticorps ampk, anticorps ampk2, anticorps prkaa, anticorps prkaa1, anticorps PRKAA2, anticorps protein kinase AMP-activated catalytic subunit alpha 2, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog, anticorps PRKAA2, anticorps Prkaa2, anticorps prkaa2.S, anticorps prkaa2

Sujet: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Poids moléculaire:

Observed_MW: 69 kDa

Calculated_MW: 62 kDa

ID gène: 5563

UniProt: P54646

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, L'effet Warburg