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Bcl-2 anticorps

BCL2 Reactivité: Humain WB, IHC, ELISA, IP Hôte: Souris Monoclonal 8A10 unconjugated
N° du produit ABIN7111910
  • Antigène Voir toutes Bcl-2 (BCL2) Anticorps
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Reactivité
    • 433
    • 188
    • 182
    • 38
    • 34
    • 22
    • 21
    • 19
    • 16
    • 16
    • 11
    • 5
    • 5
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 343
    • 116
    • 5
    • 2
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 342
    • 126
    Monoclonal
    Conjugué
    • 204
    • 33
    • 32
    • 25
    • 24
    • 14
    • 14
    • 13
    • 11
    • 11
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Bcl-2 est non-conjugé
    Application
    • 375
    • 196
    • 161
    • 111
    • 107
    • 100
    • 92
    • 66
    • 60
    • 28
    • 27
    • 25
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    Purification
    Protein A+G purification
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    B-cell CLL/lymphoma 2
    Clone
    8A10
    Isotype
    IgG2a
    Top Product
    Discover our top product BCL2 Anticorps primaire
  • Indications d'application
    WB: 1:1000-1:10000, IP: 1:500-1:5000, IHC: 1:100-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Autre désignation
    BCL2 (BCL2 Produits)
    Synonymes
    anticorps Bcl-2, anticorps PPP1R50, anticorps bcl-2, anticorps AW986256, anticorps C430015F12Rik, anticorps D630044D05Rik, anticorps D830018M01Rik, anticorps BCL-2, anticorps Bcl2, anticorps BCL2, apoptosis regulator, anticorps B cell leukemia/lymphoma 2, anticorps B-cell CLL/lymphoma 2a, anticorps B-cell CLL/lymphoma 2 protein, anticorps BCL2, anticorps Bcl2, anticorps bcl2a, anticorps BCL-2
    Sujet
    Synonyms:Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2 Background:Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
    Poids moléculaire
    26 kDa
    ID gène
    596
    UniProt
    P10415
    Pathways
    Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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