IRAK1 anticorps (pSer376)

N° du produit ABIN7138584

Détail du produit anti-IRAK1 anticorps

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Épitope: pSer376

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IRAK1

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Autre désignation: IRAK1 (IRAK1 Produits)

Synonymes: anticorps IRAK1, anticorps IRAK, anticorps pelle, anticorps AA408924, anticorps IRAK-1, anticorps IRAK1-S, anticorps Il1rak, anticorps Plpk, anticorps mPLK, anticorps RGD1563841, anticorps interleukin 1 receptor associated kinase 1, anticorps interleukin-1 receptor-associated kinase 1, anticorps IRAK1, anticorps irak1, anticorps Irak1

Sujet:

Background:

IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

Cao Z., Science 271:1128-1131(1996).
Reichwald K., Mamm. Genome 11:182-190(2000).
Jensen L.E., J. Biol. Chem. 276:29037-29044(2001).

Aliases: AA48924 antibody, Il1rak antibody, Interleukin 1 receptor associated kinase 1 antibody, Interleukin-1 receptor-associated kinase 1 antibody, IRAK antibody, IRAK-1 antibody, Irak1 antibody, IRAK1-S antibody, IRAK1_HUMAN antibody, mPLK antibody, OTTHUMP00000026014 antibody, OTTHUMP00000026015 antibody, OTTHUMP00000026020 antibody, OTTHUMP00000180621 antibody, Pelle antibody, Pelle homolog antibody, Pelle-like protein kinase antibody, Plpk antibody

UniProt: P51617

Pathways: Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades