PPM1D anticorps (AA 1-250)

N° du produit ABIN7165942

Détail du produit anti-PPM1D anticorps

Antigène: PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPM1D est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Rat

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Protein phosphatase 1D protein (1-250AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PPM1D

Antigène: PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))

Autre désignation: PPM1D (PPM1D Produits)

Synonymes: anticorps PP2C-DELTA, anticorps WIP1, anticorps AV338790, anticorps Wip1, anticorps zgc:103518, anticorps ppm1d, anticorps wu:fj44c08, anticorps zgc:55836, anticorps zgc:77316, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1D, anticorps protein phosphatase 1D magnesium-dependent, delta isoform, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1D, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1Db, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1Da, anticorps PPM1D, anticorps Ppm1d, anticorps ppm1db, anticorps ppm1d.L, anticorps ppm1da

Sujet:

Background: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates \\\'Ser-15\\\' of TP53 and \\\'Ser-345\\\' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629).

Aliases: EC 3.1.3.16 antibody, p53 induced protein phosphatase 1 antibody, p53-induced protein phosphatase 1 antibody, PP2C delta antibody, PP2C-delta antibody, PP2CD antibody, Ppm1d antibody, PPM1D_HUMAN antibody, Protein phosphatase 1D antibody, protein phosphatase 1D magnesium-dependent delta isoform antibody, Protein phosphatase 2C delta isoform antibody, Protein phosphatase 2C isoform delta antibody, Protein phosphatase magnesium dependent 1 delta antibody, Protein phosphatase magnesium-dependent 1 delta antibody, Protein phosphatase Mg2+/Mn2+ dependent 1D antibody, Protein phosphatase Wip1 antibody, Wild type p53 induced phosphatase 1 antibody, WIP 1 antibody, WIP1 antibody

UniProt: O15297

Pathways: Signalisation p53, Cycle Cellulaire