PPM1D anticorps (AA 201-300)
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- Antigène Voir toutes PPM1D Anticorps
- PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
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Épitope
- AA 201-300
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPM1D est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Homologie
- Mouse,Rat,Dog,Cow,Pig,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PPM1D
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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Cisplatin induces HepG2 cell cycle arrest through targeting specific long noncoding RNAs and the p53 signaling pathway." dans: Oncology letters, Vol. 12, Issue 6, pp. 4605-4612, (2017) (PubMed).
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Cisplatin induces HepG2 cell cycle arrest through targeting specific long noncoding RNAs and the p53 signaling pathway." dans: Oncology letters, Vol. 12, Issue 6, pp. 4605-4612, (2017) (PubMed).
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- Antigène
- PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
- Autre désignation
- PPM1D (PPM1D Produits)
- Synonymes
- anticorps PP2C-DELTA, anticorps WIP1, anticorps AV338790, anticorps Wip1, anticorps zgc:103518, anticorps ppm1d, anticorps wu:fj44c08, anticorps zgc:55836, anticorps zgc:77316, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1D, anticorps protein phosphatase 1D magnesium-dependent, delta isoform, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1D, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1Db, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1Da, anticorps PPM1D, anticorps Ppm1d, anticorps ppm1db, anticorps ppm1d.L, anticorps ppm1da
- Sujet
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Synonyms: WIP1, PP2C-DELTA, Protein phosphatase 1D, Protein phosphatase 2C isoform delta, Protein phosphatase magnesium-dependent 1 delta, p53-induced protein phosphatase 1, PPM1D
Background: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
- ID gène
- 8493
- UniProt
- O15297
- Pathways
- Signalisation p53, Cycle Cellulaire
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