PPM1D anticorps (C-Term)

N° du produit ABIN6972548

Détail du produit anti-PPM1D anticorps

Antigène: PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPM1D est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: PPM1D (protein phosphatase 1D) is required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. PPM1D antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide within the C-terminal region of human PPM1D.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur PPM1D

Antigène: PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))

Autre désignation: PPM1D (PPM1D Produits)

Synonymes: anticorps PP2C-DELTA, anticorps WIP1, anticorps AV338790, anticorps Wip1, anticorps zgc:103518, anticorps ppm1d, anticorps wu:fj44c08, anticorps zgc:55836, anticorps zgc:77316, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1D, anticorps protein phosphatase 1D magnesium-dependent, delta isoform, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1D, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1Db, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog, anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1Da, anticorps PPM1D, anticorps Ppm1d, anticorps ppm1db, anticorps ppm1d.L, anticorps ppm1da

Poids moléculaire: 70 kDa

NCBI Accession: NP_003611

Pathways: Signalisation p53, Cycle Cellulaire