DR3/LARD anticorps

N° du produit ABIN7193676

Détail du produit anti-DR3/LARD anticorps

Antigène: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DR3/LARD est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of human TNFRSF25 (AA: extra(25-199)) expressed in E. coli.

Clone: 4G12H11

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur DR3/LARD

Antigène: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Autre désignation: TNFRSF25 (TNFRSF25 Produits)

Synonymes: anticorps APO-3, anticorps DDR3, anticorps DR3, anticorps LARD, anticorps TNFRSF12, anticorps TR3, anticorps TRAMP, anticorps WSL-1, anticorps WSL-LR, anticorps Tnfrsf12, anticorps Wsl, anticorps TNFRSF25, anticorps TNF receptor superfamily member 25, anticorps tumor necrosis factor receptor superfamily, member 25, anticorps TNFRSF25, anticorps Tnfrsf25

Sujet:

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]

Aliases: DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, GEF720, WSL-LR, PLEKHG5, TNFRSF12

Poids moléculaire: 45.4 kDa

ID gène: 8718

Pathways: Apoptose