CDKN2C anticorps (AA 1-168)

N° du produit ABIN7266610

Détail du produit anti-CDKN2C anticorps

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Épitope: AA 1-168

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN2C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: [KO Validated] CDKN2C/p18-INK4C Rabbit pAb

Séquence: MAEPWGNELA SAAARGDLEQ LTSLLQNNVN VNAQNGFGRT ALQVMKLGNP EIARRLLLRG ANPDLKDRTG FAVIHDAARA GFLDTLQTLL EFQADVNIED NEGNLPLHLA AKEGHLRVVE FLVKHTASNV GHRNHKGDTA CDLARLYGRN EVVSLMQANG AGGATNLQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Classe de qualité: KO Validated

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-168 of human CDKN2C/p18-INK4C (NP_523240.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CDKN2C

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Autre désignation: CDKN2C (CDKN2C Produits)

Synonymes: anticorps CDKN2C, anticorps p18, anticorps ink4c, anticorps p18-ink4c, anticorps INK4C, anticorps p18-INK4C, anticorps C77269, anticorps INK4c, anticorps INK4d, anticorps p18INK4c, anticorps cyclin dependent kinase inhibitor 2C, anticorps cyclin-dependent kinase inhibitor 2C, anticorps cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4), anticorps CDKN2C, anticorps cdkn2c, anticorps Cdkn2c

Sujet: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.,CDKN2C,INK4C,p18,p18-INK4C,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,CDKN2C

Poids moléculaire: 18kDa

ID gène: 1031

UniProt: P42773

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases