DUSP6 anticorps

N° du produit ABIN7266848

Détail du produit anti-DUSP6 anticorps

Antigène: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp DUSP6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: DUSP6 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human DUSP6

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUSP6

Antigène: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Autre désignation: DUSP6 (DUSP6 Produits)

Synonymes: anticorps HH19, anticorps MKP3, anticorps PYST1, anticorps 1300019I03Rik, anticorps MKP-3, anticorps Mkp3, anticorps wu:fd99d09, anticorps mkp3, anticorps pyst1, anticorps DUSP6, anticorps dusp6, anticorps dual specificity phosphatase 6, anticorps dual specificity phosphatase 6 L homeolog, anticorps Dual specificity protein phosphatase 6, anticorps DUSP6, anticorps Dusp6, anticorps dusp6, anticorps dusp6.L, anticorps dus6

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014],HH19, MKP3, PYST1,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,Kinase,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Neuroscience,Signal Transduction,DUSP6

Poids moléculaire: 42kDa

ID gène: 1848

UniProt: Q16828

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades