Raptor anticorps

N° du produit ABIN7269901

Détail du produit anti-Raptor anticorps

Antigène: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Raptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: Raptor Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human RPTOR

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Raptor

Antigène: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Autre désignation: RPTOR (RPTOR Produits)

Synonymes: anticorps KOG1, anticorps Mip1, anticorps 4932417H02Rik, anticorps Rap, anticorps Raptor, anticorps mKIAA1303, anticorps RGD1311784, anticorps raptor, anticorps regulatory associated protein of MTOR complex 1, anticorps regulatory associated protein of MTOR, complex 1, anticorps regulatory associated protein of MTOR, complex 1 L homeolog, anticorps RPTOR, anticorps Rptor, anticorps rptor.L, anticorps rptor

Sujet: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.,KOG1,Mip1,RPTOR,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Regulators,RPTOR

Poids moléculaire: 43kDa/131kDa/149kDa

ID gène: 57521

UniProt: Q8N122

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Autophagy, BCR Signaling, L'effet Warburg