NRF2 anticorps (Internal Region)

N° du produit ABIN784276

Détail du produit anti-NRF2 anticorps

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Épitope: AA 445-458, Internal Region

Reactivité: Humain, Rat, Souris, Chien, Porc, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NRF2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-KHSSRLEAHL TRDE

Specificité: This antibody is expected to recognize all reported isoforms (NP_006155.2, NP_001138884.1 and NP_001138885.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, canine (Dog), Pig, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence C-KHSSRLEAHLTRDE, from the internal region of the protein sequence according to NP_006155.2, NP_001138884.1, NP_001138885.1. Genename: NFE2L2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NRF2

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Autre désignation: NFE2L2 (NFE2L2 Produits)

Synonymes: anticorps Nrf2, anticorps nfe2l2, anticorps wu:fc15g09, anticorps wu:fj67e03, anticorps NF-E2R2, anticorps NRF2, anticorps AI194320, anticorps nuclear factor, erythroid 2-like 2a, anticorps nuclear factor, erythroid 2 like 2 S homeolog, anticorps nuclear factor, erythroid 2 like 2, anticorps nuclear factor, erythroid derived 2, like 2, anticorps nuclear factor, erythroid 2-like 2, anticorps nfe2l2a, anticorps nfe2l2.S, anticorps NFE2L2, anticorps Nfe2l2

Sujet: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regulates the expression of many detoxification and antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar (CNC-bZIP subfamily of basic /leucine zipper (bZIP) transcription factors.Synonyms: HEBP1, NRF2, Nuclear factor erythroid 2-related factor 2

ID gène: 4780

NCBI Accession: NP_001138884

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling