CRTC3 anticorps

N° du produit ABIN865461

Détail du produit anti-CRTC3 anticorps

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRTC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CRTC3 expressed in E. Coli.

Clone: 5G9

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CRTC3

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Autre désignation: CRTC3 (CRTC3 Produits)

Synonymes: anticorps torc3, anticorps MGC146372, anticorps 2610312F20Rik, anticorps 6332415K15Rik, anticorps AI429792, anticorps BC011210, anticorps TORC3, anticorps RGD1309666, anticorps TORC-3, anticorps CREB regulated transcription coactivator 3, anticorps CREB regulated transcription coactivator 3 L homeolog, anticorps CRTC3, anticorps crtc3, anticorps Crtc3, anticorps crtc3.L

Sujet: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) . Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. Synonyms: TORC3, FLJ21868, CRTC3

Poids moléculaire: 68kDa

ID gène: 64784

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2