TAP2 anticorps (AA 101-185) (Biotin)

N° du produit ABIN912401

Détail du produit anti-TAP2 anticorps (Biotin)

Antigène: TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))

Épitope: AA 101-185

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PSF2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur TAP2

Antigène: TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))

Autre désignation: PSF2 (TAP2 Produits)

Synonymes: anticorps ABC18, anticorps ABCB3, anticorps APT2, anticorps D6S217E, anticorps PSF-2, anticorps PSF2, anticorps RING11, anticorps AI462429, anticorps Abcb3, anticorps Ham-2, anticorps Ham2, anticorps MTP2, anticorps Tap-2, anticorps Y1, anticorps jas, anticorps Cim, anticorps transporter 2, ATP binding cassette subfamily B member, anticorps transporter 2, ATP-binding cassette, sub-family B (MDR/TAP), anticorps TAP2, anticorps Tap2

Sujet:

Synonyms: GINS complex subunit 2, GINS2, HSPC037, PSF2_HUMAN.

Background: The GINS complex is composed of four subunits, encoded by SLD5, PSF1, PSF2, and PSF3. In S. cerevisiae, it was first identified by genetic and biochemical methods to determine factors interacting with Sld5p. Genetic interactions between these four genes also suggest that they act together. The GINS complex was independently isolated in a large scale screen for cell cycle defects. A similar complex is found in Xenopus and has a ring-like structure. In yeast, all four genes are essential and cells defective in SLD5, PSF1, or PSF2 are impaired in their ability to replicate DNA. The complex localizes to origins of DNA replication and Sld5p was previously implicated as functioning in DNA replication due to its genetic interaction with DPB11. Additional genetic and biochemical interactions of the GINS complex with Dpb11p, Dpb2p, and Sld3p suggest that it functions in some way at the replication fork during DNA synthesis.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process