PTPRJ anticorps (AA 850-890) (Alexa Fluor 555)
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- Antigène Voir toutes PTPRJ Anticorps
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
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Épitope
- AA 850-890
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PTPRJ est conjugé à/à la Alexa Fluor 555
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PTPRJ
- Isotype
- IgG
- Top Product
- Discover our top product PTPRJ Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
- Autre désignation
- Dep1/Ptprj (PTPRJ Produits)
- Synonymes
- anticorps HAAP, anticorps CD148, anticorps DEP1, anticorps HPTPeta, anticorps R-PTP-ETA, anticorps SCC1, anticorps AI450271, anticorps BET, anticorps Byp, anticorps DEP-1, anticorps PTPbeta2, anticorps Ptpb2, anticorps RPTPJ, anticorps Scc-1, anticorps Scc1, anticorps PTPRJ, anticorps acid phosphatase 1, anticorps protein tyrosine phosphatase, receptor type J, anticorps protein tyrosine phosphatase, receptor type, J, anticorps ACP1, anticorps PTPRJ, anticorps Ptprj, anticorps EUBREC_2762
- Sujet
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Synonyms: DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, DEP-1, HPTP eta, Protein-tyrosine phosphatase receptor type J, R-PTP-J, PTPRJ
Background: Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration, through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation, through KDR dephosphorylation. Negative regulator of EGFR signaling pathway, through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.
- ID gène
- 5795
- UniProt
- Q12913
- Pathways
- EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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