PEN2 anticorps (C-Term)

N° du produit ABIN929230

Détail du produit anti-PEN2 anticorps

Antigène: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEN2 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: PSENEN antibody was raised in rabbit using the C terminal of PSENEN as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PSENEN Blocking Peptide, catalog no. 33R-8714, is also available for use as a blocking control in assays to test for specificity of this PSENEN antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PEN2

Antigène: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Autre désignation: PSENEN (PSENEN Produits)

Synonymes: anticorps MSTP064, anticorps PEN-2, anticorps PEN2, anticorps Psenen, anticorps ACYPI006208, anticorps 1700023M09Rik, anticorps Pen-2, anticorps RGD1312037, anticorps CG33198, anticorps Dmel\\CG33198, anticorps anon-AE003800.1, anticorps dPen-2, anticorps psenen, anticorps pen-2, anticorps pen2, anticorps zgc:109727, anticorps presenilin enhancer gamma-secretase subunit, anticorps presenilin enhancer 2, anticorps presenilin enhancer gamma secretase subunit, anticorps Gamma-secretase subunit pen-2, anticorps presenilin enhancer, anticorps presenilin enhancer gamma secretase subunit S homeolog, anticorps PSENEN, anticorps PEN2, anticorps Psenen, anticorps pen-2, anticorps psenen.S, anticorps psenen

Sujet: Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Synonyms: Polyclonal PSENEN antibody, Anti-PSENEN antibody, presenilin enhancer 2 homolog, C. elegans antibody, MDS033 antibody, MSTP064 antibody, PEN-2 antibody, PEN2 antibody.

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway