SEMA7A anticorps

N° du produit ABIN93945

Détail du produit anti-SEMA7A anticorps

Antigène: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SEMA7A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Specificité: The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts, at low levels it is present on circulating lymphocytes.

Réactivité croisée (Details): Human

Purification: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Pureté: > 95 % (by SDS-PAGE)

Immunogène: HPB-ALL human T cell line

Clone: MEM-150

Isotype: IgM

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 4 μg/mL.
Western blotting: Non-reducing conditions.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-SEMA7A (ABIN93945)

Angelisová, Drbal, Cerný, Hilgert, Horejsí: "Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." dans: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).

Mudad, Rao, Angelisova, Horejsi, Telen: "Evidence that CDw108 membrane protein bears the JMH blood group antigen." dans: Transfusion, Vol. 35, Issue 7, pp. 566-70, (1995) (PubMed).

Détails sur SEMA7A

Antigène: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Autre désignation: CD108 (SEMA7A Produits)

Synonymes: anticorps 2900057C09Rik, anticorps CDw108, anticorps H-Sema-L, anticorps M-Sema-L, anticorps Semal, anticorps CD108, anticorps H-SEMA-K1, anticorps JMH, anticorps SEMAK1, anticorps SEMAL, anticorps sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A, anticorps semaphorin 7A (John Milton Hagen blood group), anticorps Sema7a, anticorps SEMA7A

Sujet: Semaphorin 7A (John Milton Hagen blood group),CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors –, plexin C1 and beta1 integrins.,Semaphorin 7a, JMH blood group antigen, SEMAL, SEMAK1

ID gène: 8482

UniProt: O75326

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size